![]() You can count on its help when faced with the necessity for sorting out your valuable images for all sorts of reasons. PhotoSweeper X is a dependable application with pretty smart features and an intuitive interface. PhotoSweeper is a fast, precise & super efficient tool to eliminate similar or duplicate photos even in huge photo collections. Download PhotoSweeper for macOS 10.13 or later and enjoy it on your Mac. Streamlined tool for rapidly detecting and removing duplicate images Read reviews, compare customer ratings, see screenshots, and learn more about PhotoSweeper. You can even perform a logic and simple bulk folder scan to indirectly attend to the security of your content as well, checking for copies of images and their whereabouts through their digital signature or checksum equivalents (in case they were renamed or moved) ensuring that they stay where they belong and nobody interferes with them. PhotoSweeper Lite (a lightweight version of PhotoSweeper) helps you to get rid of duplicate photos. Download PhotoSweeper Lite for macOS 10.13 or later and enjoy it on your Mac. If, for instance you frequently work with pictures for a living or for passion, whether handling regular photo albums or heavy duty design choices for professional applications. Read reviews, compare customer ratings, see screenshots and learn more about PhotoSweeper Lite. There are a lot of scenarios to think of when taking into account PhotoSweeper X's usefulness and making use of its capabilities. Solves inconveniences or awkward situations with grace, sparing considerable effort and timeĮach file benefits from a histogram and is subjected to a thorough metadata analysis showcasing numerous basic and professional details in regards to its structure, pixel composition, location on disk and originating device. It integrates a Media Browser where Apple photos, Aperture or Adobe Lightroom libraries can be imported through the dedicated button or customary drag and drop. Possibilities include comparing images by size, name, format and aspect ratio among others. These pretty much hold the fairest share in regards to the managing of supported files. Upon focusing on PhotoSweeper X notice the plethora of options and settings that settle down on in the Mac OS X system tray bar. ![]() Tips greet you at startup to help steepen the learning curve. dmg disk image file, pin it to your system by dragging and dropping the application icon into the Mac OS X Application cluster tab for handy access on future sessions. Easy installation and stable functionality, with reliable results and outputĪfter downloading and mounting the. ![]() It displays potential for cleaning and managing the system and its libraries, checking for unofficial or unknown, overlooked or hidden copies of images. Moreover, PhotoSweeper X works with your own images but can also process those located in the iPhoto library. PhotoSweeper X is a solid application that enables the tracking and removal of duplicate photos with ease, and it integrates a photo browser that displays image thumbnails and allows you to easily manage them. ![]()
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![]() ![]() The Ts have a size of 96.3 × 84.5 × 30.7 μm 3 ( x × y × z bounding box) and were fabricated in a 20 × 20 matrix (Fig. The single GDs have a size of 209.4 × 239.5 × 200.0 μm 3 ( x × y × z bounding box) and were fabricated in a 7 × 7 matrix. Pillars at the base of the GDs and Ts were designed to reduce the adhesion surface of the scaffolds to the substrate and, therefore, to facilitate their subsequent detachment. ![]() 6 Such a device for biomedical research laboratories and pharmaceutical companies, allowing for a straightforward assembling of different cell types into an in vivo-mimicking 3D co-culture system, is indeed still missing in the market and in the literature.įigures 2(a) and 2(b), respectively, show the 3D rendering (bottom and side views) of a T into a GD pocket. Reliable brain tumor-on-a-chip platforms should incorporate real-scale 3D fluidic microcapillaries for BBB modeling and biomimetic multicellular cancer models including malignant and nonmalignant cells to investigate both anticancer efficacy and potential side effects following BBB crossing. 7 The obtainment of realistic in vitro brain tumor-on-a-chip platforms is crucial to accurately select potentially valid candidate compounds in early investigation stages and, consecutively, to attenuate costs and ethical issues of unsuccessful advanced preclinical studies. 6 The vast majority of drug development fails during in vivo preclinical and clinical testing. The development of personalized anticancer compounds and nanocarriers is accompanied by the increased need for highly predictive brain cancer models to test their function. 5 To be effective and safe, CNS anticancer drugs must efficiently cross the blood–brain barrier (BBB) and selectively target the cancer cells, avoiding significant side effects on healthy cells (e.g., neurons, endothelial cells, and astrocytes). In this scenario, intensive research activity is focused on the realization and testing of innovative drugs and nanomedicines able to successfully counteract the proliferation of GBM cells. 3,4 The cell clusters infiltrated in the peritumoral niche that cannot be removed during surgery (i.e., microscopic foci) quickly develop into a new tumor due to their elevated aggressiveness and resistance to conventional anticancer treatments. GBM shows frequent and rapid recurrence, resulting in only 4% 5-year survival despite gold-standard treatments (i.e., temozolomide-based chemotherapy and radiation). 1,2 Glioblastoma multiforme (GBM) is a highly malignant, aggressive, and generally deadly brain cancer. Brain and central nervous system (CNS) cancers represent a major public health burden, with a progressive increase in incidence, deaths, and disability-adjusted life years (DALY). ![]() ![]() They also instruct the law enforcement agency to make this database available to the public. Purchase copies of accident reports at and Illinois Compiled Statutes empowers the ISP to establish and maintain a statewide database of registered sex offenders. Copies of accident reports requiring a reconstruction of the accident costs $20 each. The Sheriff’s Office charges 15 cents per page for offense reports and $5 for each accident reports. The office opens to the public from Monday to Friday between 8:00 a.m. Bring or mail the completed form to the Records Section at the address listed above. To request an incident or accident report from this agency, download, print, and complete a Freedom of Information Act Request Form. While there is no charge for viewing records, the Sheriff’s Office charges copy fees for copies of police reports. You can view these reports at the Records Office on the 1st floor of the Sheriff’s Office located at: ![]() The Records Section of the Winnebago County Sheriff’s Office maintains all police reports written by the officers of the law enforcement agency. Choose one provider on the list and contact them to schedule a fingerprinting appointment. To apply for one, visit The Bureau of Identification offers fingerprint-based background checks through a number of approved live scan fingerprint vendors. To use this service, citizens have to log in with their State of Illinois Digital IDs. To order a name-based criminal record search, visit the ISP’s CHIRP (Criminal History Information Response Process) web portal. Its Bureau of Identification offers name-based and fingerprint-based criminal record checks. The Illinois State Police provides criminal background checks for all the counties of the state. The five-year crime trend for Winnebago County also shows rising robbery (4.5%), aggravated assault (24.4%), and arson (35%) rates between 20. ![]() Reported incidences of aggravated assault include 1,894 burglaries, 5,195 thefts, 553 motor vehicle thefts, and 78 arsons. ![]() This represents a 7.1% dip in crime rate compared to 2016 and a 17.5% decline compared to the total for 2013.Ī closer look at the 2017 crime numbers for Winnebago County reveals that law enforcement agencies recorded 19 homicides, 165 rapes, 462 robberies, and 2,015 aggravated assaults. Its latest reports show that Winnebago recorded 10,384 Part I crimes in 2017. The Illinois State Police (ISP) collates and publishes crime data for all the counties in the state including Winnebago. ![]() ![]() ![]() Choose Times New Roman, and you can’t go wrong. Serifs are those small projects that finish off a letter, as in Times Roman type. Use a Serif Font:įonts are the various designs of typefaces. You can apply this same procedure to any editorial change you wish to make in an entire file at a time. To format your document all at once, press and hold Ctrl and press A to select the whole document, then use the font change box to change all the text. Make sure your formatting is set to 12 by clicking this button in Word. Twelve-point is the size of the text (letters an inch high would be 72-point type). Here’s more detail on each of these rules to help you understand how to format your manuscript in Microsoft Word. It should be the same size and font as the rest of the text. Your title should be about a third of the the page from the top and centered. The header should appear on each page after the title page.Īdditionally, agents and publishers want your name, email, address, and phone number in the top left and word count to the nearest hundred in the top right of your title page. Create a header with the title followed by your last name and the page number.If you choose to add a line between paragraphs to indicate a change of location or passage of time, center a typographical dingbat (like ***) on the line.Text should be flush left and ragged right, not justified.Indent each paragraph half an inch (setting a tab, not using several spaces).Use a serif font the most common choice is Times Roman.For more detail, refer to the “Implementing Formatting” section. If they wanted to change them, they can do it easily.Īs for how to layout your manuscript pages and determine their look, following certain general rules will make your manuscript look professional. ![]() If you’re submitting to one who specifies, naturally you want to give them what they want.īut some don’t give instructions beyond “standard manuscript format.” Then your best bet is to make your own choices, but be sure you’re consistent.įor instance, if you write out numbers between zero and nine and use digits for any after that, do it the same way every time. What size font? What typeface? How are numbers rendered - as digits or written out? Manuscript Formatting GuidelinesĮach agent and publisher may have slightly different submission guidelines - some specifying that they prefer The Chicago Manual of Style or the AP (Associated Press) Style, and some offering style specifics of their own. This includes things like whether the lines are single- or double-spaced. What is Formatting?įormatting is how your manuscript looks. ![]() Getting Started: What is a Manuscript?Ī manuscript is your work of fiction or nonfiction that you submit to a publisher or agent in the hope that someone will turn it into a published book. Need help writing your book? Click here to download my ultimate 20-step guide. ![]() ![]() Does it have agency of its own, independent of its wearer? Or is it just the perception of the one who possesses it, some strange paranoid psychosis which makes him both attached to and suspicious of the Ring? This theme will come up again in the book, and is fascinating precisely because of its ambiguity. The way he describes it, it seems as though the Ring is not an inanimate object after all, but it is sentient, surveilling everything that is going on. It’s creepy – the Ring is like an eye? An eye that watches Bilbo. But when I read that line this time, it made me stop. When the rest of the epic fills your reminiscences, it is easy to overlook early details like this. Sometimes I have felt it was like an eye looking at me.” Had it not been for Gandalf’s intervention, Bilbo Baggins might have been wandering in the wilderness with the Ring, with no protection, and – unbeknownst to him – in mortal danger.Īs for that Ring, Bilbo’s own words corroborate Gandalf’s suspicions about it: If we didn’t know him better, we would wonder why it matters so much that Bilbo wants to keep his ring – why should he not? But we innately trust Gandalf’s reasons, and thank goodness he prevails in the end. It is a surprise, therefore, to see Gandalf raising his voice against the old hobbit, it’s a sudden jolt after the light-hearted Shire-talk and the Party. His cantankerousness was never a real threat. ![]() Moreover, we always saw Gandalf sticking up for Bilbo, and we got used to seeing the paternalistic side to him in the prequel. Tolkien did such a good job in setting Gandalf up as a figure of wisdom and confidence in The Hobbit, that when he is troubled by something, the reader knows the matter is serious. The two traits, or rather curses, bestowed by the Ring on its owner – unnaturally long life and covetousness – are exposed to the reader via Gandalf. It is Gandalf’s reaction in particular that raises the alarm for the reader – he watches Bilbo, “curiously and closely”, and when Bilbo calls the Ring his “precious”, it is Gandalf who reminds him and us that “it has been called that before”. When Bilbo uses it again to disappear from his Birthday Party, we don’t think much of it it is only when Bilbo has his unsettling quarrel with Gandalf at Bag End that we sense something is not quite right. ![]() One final thing we took note of from The Hobbit was that it was once obsessively possessed by Gollum. This power was used by Bilbo to help him and his company get out of several tricky situations, and thus we have no reason to fear the Ring, rather we are inclined to see it as something useful. Despite its plain appearance, it also has the extraordinary capacity to make the wearer invisible. All we know about it before now is that it is a plain gold band, picked up by Bilbo in the dark depths of the misty mountains. It is in this chapter that we get our first glimpse of the power and evil influence of the Ring. The morning after the night before – Drawing with ink and wide nib ![]() ![]() ![]() The amount of medicine that you take depends on the strength of the medicine. If your dose is different, do not change it unless your doctor tells you to do so. The following information includes only the average doses of this medicine. Follow your doctor's orders or the directions on the label. The dose of this medicine will be different for different patients. If you have any questions about this, check with your doctor. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If your doctor ordered an occlusive dressing or airtight covering to be applied over the medicine, make sure you know how to apply it. ![]() If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor. With the lotion, shake it well before using.ĭo not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor. Wash your hands with soap and water before and after using this medicine.Īpply a thin layer of this medicine to the affected area of the skin. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should only be used for skin conditions that your doctor is treating. If it does get on these areas, rinse it off right away with water. Do not use it on skin areas that have cuts, scrapes, or burns. This medicine is for use on the skin only. ![]() ![]() ![]() It was even announced in February 2022 that Pine and the rest of the main cast (aside from Anton Yelchin, who died in 2016) would be back for Star Trek 4, though it was later revealed that the actors hadn’t actually been approached about the project. Abrams rebooted the Star Trek movies with great success in 2009, but the franchise soon began struggling. ![]() Spock keeping him in check as a vengeful Romulan from the future creates black holes to destroy the Federation one planet at a time. Kirk tries to live up to his father's legacy with Mr. It has been six years since Star Trek fans have seen the USS Enterprise on the big screen, but they will soon get to see it again as producer JJ Abrams announced at ViacomCBS. In the years since though, Star Trek 4 has cycled through various directors and writers, including WandaVision’s Matt Shakman stepping away so he can focus on helming Fantastic Four. With Chris Pine, Zachary Quinto, Leonard Nimoy, Eric Bana. Star Trek 4 has been in the works sine shortly before Star Trek Beyond opened to the public, with the plan at the the time being for the story to revolve around Chris Pine’s James Kirk meeting his father, Chris Hemsworth’s George Kirk, who died at the beginning of 2009’s Star Trek mere moments after James was born. I will say it’s the first time that we have a story that feels as compelling as the first one. While there’s still no timetable on when Star Trek 4 will arrive, Abrams shared this comment about where things stand with it in an Esquire profile about Chris Pine, who plays James Tiberius Kirk in the Kelvin timeline: For 2016’s Star Trek Beyond, he passed the directing baton to Justin Lin, but he remained involved with that movie as an executive producer and holds that same position for Star Trek 4. It would be something of a miracle if you’d got this far without realising the JJ Abrams-directed Star Wars film The Force Awakens (2015) is just around the corner, with opening night December. Abrams rebooted the Star Trek franchise in 2009 from the director’s chair with the aptly-named Star Trek, and he reprised those helming duties for 2013’s Star Trek Into Darkness. ![]() ![]() ![]() Or maybe I wouldn’t have written one at all. ![]() All I could think was: if I’d known I was going to have to say this whole book out loud, I would have written a better one. I narrated my own audiobook in 2014, an experience that I described at the time as being akin to an exorcism: three long days in a dark room, tripping through the minefield of my own words. Narration may sound like an easy way to make money – you just sit there and read – but I can assure you, it isn’t. Some of the biggest British voices in audiobooks belong to faces you might not recognise, but may well have seen – on stage, on Coronation Street, or in any number of Carry On films. In the US, 81-year-old actor George Guidall is considered narration’s undisputed heavyweight champion: his baritone voice has graced more than 1,300 audiobook recordings, including works by Dostoevsky, Jonathan Franzen and Stephen King. The real professionals, however, are people you might not have heard of. “I’m so impressed with professional readers,” says Bryson, “the Martin Jarvises of this world, or people like Stephen Fry, who can really bring extra dimensions to it.” Any movement creates extraneous noise: fabric rustling, chair creaking, foot tapping’īut while technology has transformed the industry, it still relies on an army of audiobook narrators to meet the demand. Today, Audible’s catalogue contains more than 400,000 titles in 2018, its members downloaded nearly three billion hours of content. In the 1990s, before the iPod was launched, Audible was selling a proprietary digital media player that held about two hours of audio downloaded from its online library. This growth has largely been driven by the rise of Audible, the Amazon-owned platform that dominates the digital audiobook market through its subscription streaming service, though there are other players, including Storytel, which operates largely in Scandinavian countries. In the US, audiobook downloads generate revenue of close to a billion dollars annually. In a climate where print and ebook sales are stagnant, the UK audiobook market rose to £69m in 2018, an increase of 43% on the previous year. In the two decades since Bryson recorded his first narration, the audiobook market has grown from a publishing industry side hustle into a huge global business. “You know what it’s like when you’re writing – you don’t think about anything, really, except trying to get words right to yourself on the page.” “Now I’ve probably worked with five or six producers,” he says, “and they’re all really kind, and they’re always very encouraging, but I can’t help feel that I should be better at this, that I should be able to pronounce the words in my own book.” Does he not realise by now that when he commits a word like glomerulonephritis to print, he will eventually have to record it? “You would think so, but no,” he says. ![]() Bryson’s audiobook experience goes back 20 years, when he was living in New Hampshire and the nearest recording studio was in the neighbouring state of Vermont. ![]() ![]() ![]() This beer sits in the upper echelon of calorie content, with other high-calorie beers such as Dogfish Head 120 Minute IPA (240 calories), Rogue Imperial IPA (220 calories), and BrewDog Lost Rhino Tall Tale Imperial Stout (220 calories) following close behind. Additionally, it has a mouthwatering aroma of caramel, maple and chocolate. 5 percent ABV and 284 calories per 12 oz. The beer that has the most calories is Sam Adams Triple Bock. However, it’s important to keep in mind that all beer, including IPA, contains a certain level of alcohol, so it should still be consumed in moderation for the most health benefits. In terms of other health benefits, some IPA styles can contain probiotics, while others may contain higher amounts of antioxidants. This may mean that if you are looking for a healthier option in terms of alcohol intake, IPA is a better choice. Similarly, IPA is a craft beer that is lighter in color and flavor than traditional beer, so it typically has a lower alcohol percentage. On the other hand, beer contains vitamin B, folate, and other essential minerals that are beneficial for the body. ” Beer is typically higher in calories than IPA, so it may not be the best choice if you’re watching your calorie intake. It depends on your definition of “healthy. Furthermore, the ingredients list for a Starbucks London Fog is reflective of this as it only includes a combination of Earl Grey tea, steamed milk, and vanilla syrup.ĭepending on your preferred level of sweetness, you can always opt to add more sugar or add-in sweeteners like simple syrup, honey, or agave syrup to tailor the drink to your tastes. How much sugar is in a Starbucks London Fog?Ī Starbucks London Fog contains 0 grams of sugar. It is similar to a latte or cappuccino but has a unique flavor profile that sets it apart. The beverage is topped with a thin layer of froth and a light dusting of cinnamon or nutmeg, which results in its distinctive flavor. Originally made with earl grey tea, the London Fog also sometimes includes a shot of vanilla. It is a warm, aromatic beverage made with espresso or black tea, steamed milk, and flavored syrup. The end result is a satisfying cup of tea that can be enjoyed as is or topped with a sprinkle of cinnamon for a little extra spice, and makes for a delicious and guilt-free morning or afternoon pick-me-up. However, the skinny version of this classic beverage is made with non-fat milk and no added sweeteners or syrups, making it lighter and healthier than the original. 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